https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Cancer stem cells are underestimated by standard experimental methods in clear cell renal cell carcinoma https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24837 Wed 10 Nov 2021 15:13:34 AEDT ]]> Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25061 80 %. Culture in serum-free conditions selected for growth of normal renal proximal tubule epithelial cells. Transcriptional profiling of ccRCC and matched normal cell cultures identified up- and down-regulated networks in ccRCC and comparison to The Cancer Genome Atlas confirmed the clinical validity of our cell cultures. Conclusions: The ability to establish primary cultures of ccRCC cells and matched normal kidney epithelial cells from almost every patient provides a resource for future development of novel therapies and personalized medicine for ccRCC patients.]]> Fri 03 Dec 2021 10:33:37 AEDT ]]>